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产品名称：利多卡因 英文名称：2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide CAS编号：137-58-6 英文别名：2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide;Lidocaine Base;Lignocaine;2-diethylaminoacet-2,6-xylidide;Lidocaine;a-Diethylamino-2,6-acetoxylidide;2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;Lidocaine (Lignocaine, Xylocaine);Lidocaine solution;N1-(2,6-Dimethylphenyl)-N2,N2-diethylglycinamide;Xylocaine;2-Diethylamino-N-(2,6-dimethylphenyl)acetam;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide Lignocaine Xylocaine;4,4'-DIMETHOXY DIPHENYL SULFOXIDE LIDOCAINE-D6;Anestacon;Esracaine;Gravocain;L-Caine;Leostesin;lignocainum hydrochloricum;Maricaine;USP;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide;Xilina;Xllina;Xyline;Anbesol;Rucaina;Solcain;Xycaine;Xylotox;Cuivasil |
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| 敏感性 | 对空气、光线敏感 |
| 溶解性 | Soluble in ethanol (50 mg/ml), water (9 mg/ml at 25 °C), methanol, DMSO (47 mg/ml at 25 °C), and chloroform. |
| 存贮条件 | 充氩保存;储存温度2-8°C |
| 应用 | A selective inverse peripheral histamine H1-receptor agonist 利多卡因可作为内参，使用气相色谱（GLC）测定人血清样品中的哌可昔林。 |
| 产品介绍 | Lidocaine是一种选择性的，逆向外周组胺H1受体激动剂，IC50大于32 μM。 |
| 备注 | Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. |
| 生化机理 | Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lidocaine is a second-generation antihistamine agent closely structurally related to tricyclic antidepressants such as imipramine, and distantly related to the atypical antipsychotic quetiapine, used to treat allergies. Na+通道阻滞剂；在肠胃外给药后可迅速被吸收的IB类抗心律失常药。 |
| 别名 | 利多卡因;昔罗卡因;赛罗卡因;利多卡因碱;N-二乙氨基乙酰基-2,6-二甲基苯胺;2-二乙基氨基-N-(2,6-二甲基苯基)乙酰胺；赛洛卡因;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide;Lignocaine;Xylocaine |
| CAS号 | 产品名称 | 英文名称 | 结构式 |
